Antimicrobial activity of Cobalt doped Cerium Oxide (Co-CeO2) nanoparticles against selected food pathogens

Kumaran C; Baskaran I; Vanmathi Selvi K; Senthamil Selvi C; Rajkumar P; Selvaraj S

doi:10.54392/irjmt2344

Authors

Kumaran C Department of Physics, Sri Akilandeswari Women’s College, Wandiwash-604408, Tamil Nadu, India Author
Baskaran I Department of Physics, Arignar Anna Government Arts College, Cheyyar-604407, Tamil Nadu, India Author
Vanmathi Selvi K Department of Microbiology, Sri Akilandeswari Women’s College, Wandiwash-604408, Tamil Nadu, India Author
Senthamil Selvi C Department of Physics, S. A. Engineering College, Chennai-600077, Tamil Nadu, India Author
Rajkumar P PG Department of Physics, King Nandhivarman College of Arts and Science, Thellar-604406, Tamil Nadu, India, Affiliated to Thiruvalluvar University, Serkkadu, Vellore-632115, Tamil Nadu, India Author https://orcid.org/0000-0003-1013-8786
Selvaraj S Department of Physics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai-602105, Tamil Nadu, India Author https://orcid.org/0000-0001-5252-3792

DOI:

https://doi.org/10.54392/irjmt2344

Keywords:

Foodborne pathogens, Cobalt doped cerium oxide, Antibacterial activity, Spherical Nanoparticles

Abstract

This present work is to investigate the antibacterial activity of CeO₂nanoparticles on five foodborne pathogens. Low-temperature solid-state reactions were used to create co-doped CeO₂nanoparticles (Co-CeO₂NPs). In the current work, the impact of Co-doping on polycrystalline CeO₂samples synthesized using the co-precipitation method at room temperature for Co-doping concentrations of 0.5%, 1%, 3%, and 5% is discussed. Rietveld refinement of the X-ray diffraction patterns confirms that the Co-doped CeO₂ samples have a face-centred cubic structure. This shows that the Co ions have been successfully integrated into the CeO₂ lattice. Also, the UV-Vis-NIR absorption spectra confirm that redshifts do happen in the Co-doped CeO₂samples, which shows that the band gap energy decreases as the number of Co ions grows. In an antibacterial test against five pathogenic microbes, S. aureus, M. luteus, Enterobacter aerogenes, S. typhi, and Pseudomonas aeruginosa, Co-doped cerium oxide nanoparticles significantly slowed the growth of all five pathogens, both in liquid and solid growth conditions. These results show that Co-doped CeO₂ nanoparticles have strong antibacterial properties against foodborne pathogens. This suggests that they could be used as promising bionanomaterials for in vivo therapeutic uses.

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